Spot Diagnosis

A 26-year-old malnourished woman presented with a 4-day history of mouth pain and a 3-month history of fatigue, general malaise, and palpitations. What is the most likely diagnosis?

A 69-year-old man was referred for the evaluation of changes to his fingernails. Physical examination revealed multiple white lines on the fingernails. What is the most likely cause of this presentation?

Erythematous Concentric, Raised, Serpiginous Skin Lesions An 83-year-old man was evaluated for a 1-year history of a pruritic, progressively worsening migratory rash, with associated weakness and a 5-kg weight loss.…

A 47-year-old woman presented with a 2-week history of widespread, painful lesions on her trunk and limbs. What is the diagnosis ?

What could cause nail changes like this ? ANSWER

A healthy 69-year-old man with osteoarthritis of the knees presented with a 2-week history of mottled darkening of the skin on the left thigh. On examination, there was a reticular, reddish-brown, pruritic, nontender, macular, nonblanching discoloration around the medial aspect of his left knee, with a few superficial erosions.

This patient presented with a 10-day history of left foot discoloration that resolved with elevation. What is the most likely diagnosis?

A 21-year-old woman with human immunodeficiency virus infectionpresented with a 1-week history of fever, chest pain, and hemoptysis. What's the Diagnosis based on this Chest X-Ray ?

Black Cutaneous Lesions A healthy 65-year-old man presented with a 4-month history of left flank pain and nocturia. These lesions developed over 1 to 2 years. What is the most…

Unilateral Leg Swelling and Bluish Discoloration An 85-year-old woman with newly diagnosed metastatic non–small-cell lung cancer was admitted for pain control. Two days after admission, unilateral leg swelling and bluish…