Imaging of Acute Pancreatitis: to Image or Not to Image

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Acute Pancreatitis - Causes, Pathology, Symptoms and Signs, Investigations, Management and Complications

In patients with typical symptoms and diagnostic laboratory tests, CT or MR imaging is not required to confirm the diagnosis of acute pancreatitis. CT or MR imaging are primarily used to detect complications of acute pancreatitis...

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The Pain in Chronic Pancreatitis

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Chronic Pancreatitis - Pathology, Symptoms and Signs, Investigations, Management

Chronic pancreatitis occurs when there is irreversible and progressive destruction of the pancreas. While the etiology of the pain in chronic pancreatitis is not well understood, it is most likely due to: chronic inflammation, altered nociception and tissue ischemia

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Evaluation of Jaundice

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Causes of jaundice

Jaundice (icterus) is the yellow discoloration of the skin, sclera, and mucosae, which is detectable when serum bilirubin concentrations exceed approximately 2.5 mg/dL. Jaundice can arise as a result of increased red blood cell (RBC) breakdown, disordered bilirubin metabolism, or reduced bilirubin excretion.

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Boerhaave Syndrome: Not all Life-threatening Chest Pain Involves the Heart and Lungs

Read more about the article Boerhaave Syndrome: Not all Life-threatening Chest Pain Involves the Heart and Lungs
Boerhaave Syndrome - Causes, Symptoms, Diagnosis, Treatment

Boerhaave syndrome is a spontaneous rupture of the esophagus. It usually results from barotrauma related to retching or any sudden increase in intraabdominal pressure against a closed glottis.

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Anticipate Bleeding and Reverse Coagulopathies in Liver Failure

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Laboratory Abnormalities and Treatment of Coagulopathy in Liver Failure

Blood clotting in the setting of chronic liver disease is complex and may result in a net prothrombotic or antithrombotic state. Complicating this situation is the lack of accurate lab assays to measure the net thrombotic state in liver disease patients.

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When an Appendicitis Doesn’t Follow the Rules

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Appendicitis - Pathogenesis and Clinical Findings

Classic symptoms of appendicitis include pain that is initially vague and periumbilical followed by a more localized parietal pain in the right lower quadrant. Only 50% of people present with these classic symptoms; in the other 50%, appendicitis can be difficult to diagnosis.

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