Spot Diagnosis

A 19-year-old man presented with pedal oedema and facial puffiness of 3 months' duration. He denied history of orthopnoea, paroxysmal nocturnal dyspnoea, oliguria, haematuria, fever, sore throat, joint pains, rashes, exposure to heavy metals, or any drug abuse.

Painful Skin Lesions A 61-year-old who was receiving long-term treatment with prednisone for refractory idiopathic thrombocytopenic purpura required a dose increase after a large decrease in platelet count (6×109/L). He…