Spot Diagnosis

What could cause nail changes like this ? ANSWER

A healthy 69-year-old man with osteoarthritis of the knees presented with a 2-week history of mottled darkening of the skin on the left thigh. On examination, there was a reticular, reddish-brown, pruritic, nontender, macular, nonblanching discoloration around the medial aspect of his left knee, with a few superficial erosions.

This patient presented with a 10-day history of left foot discoloration that resolved with elevation. What is the most likely diagnosis?

A 21-year-old woman with human immunodeficiency virus infectionpresented with a 1-week history of fever, chest pain, and hemoptysis. What's the Diagnosis based on this Chest X-Ray ?

Black Cutaneous Lesions A healthy 65-year-old man presented with a 4-month history of left flank pain and nocturia. These lesions developed over 1 to 2 years. What is the most…

Unilateral Leg Swelling and Bluish Discoloration An 85-year-old woman with newly diagnosed metastatic non–small-cell lung cancer was admitted for pain control. Two days after admission, unilateral leg swelling and bluish…

A 52-year-old man with diabetes reported a 3-month history of a pretibial rash during a routine visit. The lesions had begun to ulcerate and bleed but were not pruritic or painful.

This 9-year-old boy presented with a two-day history of right shoulder pain after an upper respiratory tract infection. What is the cause of the abnormality demonstrated?

37-year-old man with Dyspnea 37-year-old man with known end-stage renal disease and chronic uraemic pericardial effusion presented with gradually worsening dyspnoea and orthopnoea, 4 days after a nephrectomy to control…

Pleural aspiration from a 56-year-old man, who presented with a massive right pleural effusion, yielded purely black coloured fluid. This fluid was determined to be an exudate with very high…