Hypokalemia ECG Changes [With Examples]

  • Post category:ECGs

ECG Changes in Hypokalemia

  • First-degree atrioventricular block (prolonged PR interval)
  • Depression of the ST segment
  • Small T waves (flattening and inversion)
  • Prominent U waves
  • Long QU interval that appears as long QT interval because of fusion of T and U waves

Hyperkalemia and Hypokalemia ECG Changes
Hyperkalemia and Hypokalemia ECG Changes

Complications of Severe Hypokalemia seen on the ECG

  • Frequent premature atrial and ventricular ectopics
  • Supraventricular tachyarrhythmias: Atrial Fibrillation , atrial flutter, atrial tachycardia
  • Life-threatening ventricular arrhythmias (VT , VF)

If hypokalaemia is suspected, assess the patient for symptoms (e.g. muscle weakness, cramps) and review the treatment chart. Although many conditions can lead to hypokalaemia, the commonest cause is diuretics.

Example 1

ECG of Hypokalemia with Long QT (QU interval) interval, U waves and widespread ST depression due to familial hypokalemic paralysis
ECG of Hypokalemia with Long QT (QU interval) interval, U waves and widespread ST depression due to familial hypokalemic paralysis

  • Long QT interval, more precisely long QU interval, with evident U waves best seen in Leads V2 to V5.
  • ST Segment Depression in all leads except in aVR.

This young man has had numerous episodes of profound weakness due to “familial hypokalemic paralysis“. His potassium level in the ED was 1.5 mmol/L.

Example 2

ECG of Hypokalemia with down-up T waves, long QT interval and U waves due to Anorexia Nervosa and Diarrhea
ECG of Hypokalemia with down-up T waves, long QT interval and U waves due to Anorexia Nervosa and Diarrhea
  • Sinus rhythm
  • Right Axis Deviation
  • P waves consistent with Right Atrial Enlargement (RAE) – reported to occur with Hypokalemia
  • T waves with down-up morphology with long QT interval because of the presence of U waves (seen in Hypokalemia)

This young woman had Anorexia Nervosa and weighed 90 lbs (40kg) and had Diarrhea from daily intake of 30 laxative tablets which resulted in Hypokalemia. Her serum potassium was 1.6 mmol/L.

Example 3

Hypokalemia with Prolonged QT Interval that led to Ventricular Tachycardia (Torsades de pointes)
Hypokalemia with Prolonged QT Interval that led to Ventricular Tachycardia (Torsades de pointes)
  • Sinus rhythm approximately 100/min
  • Prolonged PR Interval (First Degree AV Block)
  • ST Depression in multiple leads
  • U Waves best seen in precordial leads
  • Prolonged QT (QU) Interval