(B) Thickening and segmental dilatation of ascending aorta, arch, and descending thoracic aorta on CT angiogram.
(C) Dense acute necrotising suppurative inflammation comprised of neutrophil and nuclear debris on skin biopsy (haematoxylin and eosin stain, 20X).
(D) Healed ulcer with residual scarring after treatment.
A 26-year-old woman presented with history of recurrent superficial thrombophlebitis on all limbs, deep vein thrombosis involving the lower limbs, a fever, and a large non-healing ulcer on the left cubital fossa. There was no history of an oral or genital ulcer, eye involvement, or altered bowel habits.
A whole body ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) PET showed ¹⁸F-FDG avid circumferential wall thickening of the aorta and its major branches.
What’s the most likely diagnosis ?
- Behcet’s syndrome
- Cutaneous tuberculosis with aortitis
- Pyoderma gangrenosum with Takayasu arteritis
- Inflammatory bowel disease with Sweet syndrome
