ECG Case 284 Interpretation

This post is an answer to the ECG Case 284

  • Rate: 42 bpm
  • Rhythm:
    • Irregular
    • No visible p waves
  • Axis: Normal
  • Intervals:
    • QRS – Prolonged (200ms)
    • QT – 760ms (QTc Bazette 640 ms)

  • Segments:
    • ST Elevation in lead aVR
    • ST Depression in leads II, III, aVF, V2-6
  • Additional:
    • Deep T wave inversion in leads II, III, aVF, V1, V3-5
    • Osbourne-J waves best seen in infero-lateral leads
    • ST morphology in lead V1 has ‘brugada’ appearance

Interpretation

Main differentials for these ECG features include:

  • Hyperkalaemia – known T1DM altered conscious level could be associated with DKA
  • Metabolic disturbance – severe acidaemia
  • Hypothermia – slow AF, J waves
  • Drug toxicity – ? sodium channel blocker – ‘Brugada’ pattern in V1

What happened next ?

The patient was found obtunded and further history suggested a drug ingestion including a tricyclic antidepressant and paracetamol. He was severely hypothermic, core temp 25°C, with a  significant metabolic disturbance:

  • pH 6.9
  • K 7.2 
  • HCO3 7 
  • U 10.6 
  • Creat 267
  • Lactate 26

The patient was successfully resuscitated but unfortunately following his ICU admission he developed multi-organ failure and failed to respond to organ replacement and increasing vasopressor administration.

READ MORE: ECG Interpretation – All you need to know