Mees’ lines

This is an answer to the case – Nail Sign observed in a 19 year old man

Renal biopsy was consistent with focal segmental glomerulosclerosis.

The Nail Changes called Mees’ lines (also known as Aldrich or Reynolds’ lines) are transverse white bands on the nail plate laid down during periods of stress.

Common associations are:

  • Poisioning (arsenic, thallium, fluorosis)
  • Severe infection
  • Renal disease
  • Cardiac failure
  • Malignant disease.

Mees’ lines are indicative of systemic pathology and serve as a useful clinical guide.

Mees' lines
Mees’ lines