Spot Diagnosis

His medications were apixaban, ramipril, bisoprolol, amlodipine, and amiodarone. Physical examination showed discoloration of his nose, cheeks, and forehead.

A 7-year-old girl presented to the emergency department with a 2-week history of fever and with several days of painful blisters on her arms, legs, and face. Two weeks earlier, she had completed a course of penicillin for tonsillitis.

A 27-year-old primigravid woman was admitted with new-onset diabetes and hypertension at 32 weeks of gestation. She had worsening proximal muscle weakness, striae, and facial plethora for several months.

A 64-year-old man presented to the oral medicine clinic with a painful, smooth, red tongue and a burning sensation around his lips that had developed 6 months earlier. No deficits were found on neurologic examination.

A 42-year-old man who was undergoing treatment for non-Hodgkin’s lymphoma presented to the oncology clinic with changes in his fingernails. What is the most likely underlying cause of this presentation?

A 70-year-old woman presented with a 1-week history of dizziness and generalized rash following the onset of a viral respiratory tract infection. On physical examination, she had a generalized, macular, nonblanching, purplish rash.

A 30-year-old man presented with a rash on his face, hands, and feet. He had a history of HIV with a CD4+ T-cell count of 374 per cubic millimeter. Physical examination showed circinate lesions on the palms, soles, and face and patchy alopecia.

A 37-year-old man presented with a 4-year history of excessive sweating, headaches, and joint pain. His wife had also noticed increasing skin folds on his scalp. He also had enlarged feet and hands and a protruding lower jaw.

What could be the most likely diagnosis for this incidental finding on an MRI?

An 84-year-old man presented with fever, malaise, and discoloration and pain in his fingers and toes ongoing for 2 weeks. What is the most likely diagnosis?