Antibiotics – Inhibitors of Tetrahydrofolate Synthesis

Read more about the article Antibiotics – Inhibitors of Tetrahydrofolate Synthesis
Antibiotics - Inhibitors of tetrahydrofolate synthesis

Most bacteria do not have a requirement for folate, because they are capable of synthesizing folate, more precisely dihydrofolate DHF, from precursors. Selective interference with bacterial synthesis of Tetrahydrofolate (THF) can be achieved with sulfonamides and trimethoprim.

Continue ReadingAntibiotics – Inhibitors of Tetrahydrofolate Synthesis