Antibiotics acting on DNA
Deoxyribonucleic acid (DNA) serves as a template for the synthesis of nucleic acids. Ribonucleic acid (RNA) executes protein synthesis and thus permits cell growth. Synthesis of new DNA is a…
Deoxyribonucleic acid (DNA) serves as a template for the synthesis of nucleic acids. Ribonucleic acid (RNA) executes protein synthesis and thus permits cell growth. Synthesis of new DNA is a…
Unilateral Leg Swelling and Bluish Discoloration An 85-year-old woman with newly diagnosed metastatic non–small-cell lung cancer was admitted for pain control. Two days after admission, unilateral leg swelling and bluish…
Approach all EKGs systemically. Always note: rate, rhythm, QRS axis, complexes and intervals, chamber enlargement, ischemia/infarction, compare with prior EKG.
The classic presentation of an acute coronary syndrome (ACS) is that of an older age male smoker with hypertension who reports exertional chest pressure that radiates to the left upper…
63 Old Women presented with palpitations and this ECG. What abnormalities do you see and what is the rhythm ?
The Approach (Questions): Is the dizziness true vertigo? If so, is it central or peripheral vertigo? Is the vertigo intermittent - likely benign? Constant vertigo is either acute peripheral vestibulopathy (APV) or a posterior circulation/cerebellar CVA
Most bacteria do not have a requirement for folate, because they are capable of synthesizing folate, more precisely dihydrofolate DHF, from precursors. Selective interference with bacterial synthesis of Tetrahydrofolate (THF) can be achieved with sulfonamides and trimethoprim.
Intraosseous (IO) access can serve as a lifesaving alternative to intravenous (IV) access, especially in the crashing hypovolemic patient. The noncollapsible medullary space of bone is a reliable entry point into the vascular system in patients with difficult or delayed IV access.
Remove clothing (operative for adherent clothing), Stop burning, Provide first aid (avoid hypothermia with overuse of water to decontaminate wounds), Asses for other injuries, asses burn severity (below), consider transfer
Inhibitors of cell wall synthesis are suitable antibacterial agents, because animal and human cells lack a cell wall. They exert a bactericidal action on growing or multiplying germs.