Correct answer = Protamine sulfate.

Excessive bleeding may be managed by ceasing administration of heparin or by treating with protamine sulfate. Infused slowly, protamine sulfate combines ionically with heparin to form a stable, inactive complex.

Aminocaproic acid and tranexamic acid are approved for the treatment of hemorrhage but do not specifically reverse the effects of heparin to stop bleeding. Vitamin K1 is used to help reverse the effects of warfarin-induced bleeding.

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