This article is an answer to the Case – Painful Hemorrhagic Bullae After Eating Raw Seafood
At the time of presentation, hemorrhagic bullae measuring 3.5 by 4.5 cm had developed on the palm of his left hand, and erythematous swelling with confluent tense bullae and ecchymoses had developed on the dorsum of the hand and forearm.
Surgical intervention was performed urgently, and Vibrio vulnificus was isolated from the bullae. Postoperatively, the patient received intravenous ceftazidime and ciprofloxacin. The patient did well after the surgery and was discharged home.
V. vulnificus can cause skin infections after wound exposure to contaminated seawater, as well as primary septicemia through the consumption of contaminated raw or undercooked seafood.
Patients with immunocompromising conditions, including chronic liver disease and cancer, are at increased risk for infection and complications. Despite treatment, the skin lesions progressed to deep necrotic ulcers, and amputation of the left forearm was performed 25 days after presentation.
- François Barbier, Paul-Louis Woerther, Jean-François Timsit. (2023) Rapid diagnostics for skin and soft tissue infections: the current landscape and future potential. Current Opinion in Infectious Diseases 36:2, 57-66.
- Jun-Yang Ma, Xin-Kun Zhu, Ren-Ge Hu, Ze-Zheng Qi, Wen-Chao Sun, Zhi-Peng Hao, Wei Cong, Yuan-Huan Kang. (2023) A systematic review, meta-analysis and meta-regression of the global prevalence of foodborne Vibrio spp. infection in fishes: A persistent public health concern. Marine Pollution Bulletin 187, 114521.
- Yue Gong, Young Ran Kim. (2023) Therapeutic potential of otilonium bromide against Vibrio vulnificus. Research in Microbiology 174:1-2, 103992.
- Thomas Theo Brehm, Susann Dupke. (2022) Infektionen mit Nicht-Cholera-Vibrionen. Public Health Forum 30:4, 252-255.
- Shuaijun Zou, Qianqian Wang, Peipei Zhang, Bo Wang, Guoyan Liu, Fuhai Zhang, Jie Li, Fan Wang, Beilei Wang, Liming Zhang. (2022) Biomimetic Nanosponges Enable the Detoxification of Vibrio vulnificus Hemolysin. International Journal of Molecular Sciences 23:12, 6821.