Topics Archives - Page 3 of 15 - Manual of Medicine

Sensory and Motor Neurologic Deficits: Approach and Evaluation

Motor Neurologic Deficit and Neurologic Muscle Weakness - An Algorithm for the Initial Workup

Post category:Neurology
Post published:January 14, 2022

Sensory neurologic deficits include: Hyperesthesias (increased pain, touch, or vibration); Hypalgesia (decreased sensitivity to painful stimuli); Paresthesia (abnormal sensation of the skin like tingling, pricking, chilling, burning, numbness); Anesthesia (complete loss of pain, temperature, touch, and vibration sense). Sensory and Motor Neurologic Deficits can result from disease occurring anywhere along the pathway from the skin or muscle to the brain and back.

The Pain in Chronic Pancreatitis

Chronic Pancreatitis - Pathology, Symptoms and Signs, Investigations, Management

Post category:Gastroenterology
Post published:January 11, 2022

Chronic pancreatitis occurs when there is irreversible and progressive destruction of the pancreas. While the etiology of the pain in chronic pancreatitis is not well understood, it is most likely due to: chronic inflammation, altered nociception and tissue ischemia

Lymphadenopathy and Splenomegaly: Approach and Evaluation

The Causes of Splenomegaly

Post category:Hematology and Oncology
Post published:January 11, 2022

Splenomegaly is often a focus of short case examinations since many of its causes are chronic. Lymphadenopathy may be localized or generalized...

Acalculous Cholecystitis: no Stones, no Problems?

Risk Factors Associated with Acalculous Cholecystitis

Post category:Gastroenterology
Post published:January 7, 2022

The pathophysiology of acalculous cholecystitis is thought to start with an acute or acute-on-chronic condition that leads to endothelial injury and gallbladder ischemia.

Anemia: Approach and Evaluation

Evaluation of Patients with Anemia

Post category:Hematology and Oncology
Post published:January 3, 2022

A patient is anemic when the hemoglobin concentration in the blood is less than 13 g/dL (or hematorcit [Hct] less than 39%) in men and 12 g/dL (or Hct less than 36%) in women. The size of the red blood cells gives important clues as to the likely underlying abnormality.

Ascending Cholangitis aka Biliary Sepsis

Ascending Cholangitis - Pathogenesis and Clinical Findings

Post category:Gastroenterology
Post published:December 28, 2021

A classic “you’ll miss it if it’s not on your differential,” ascending cholangitis refers to a bacterial infection of the biliary system, requiring both obstruction and bacterial colonization of the biliary tract.

Approach to the Patient with Vertigo and Dizziness

Diagnostic algorithm for dizziness and vertigo

Post category:Neurology
Post published:December 23, 2021

True vertigo is the false perception (illusion) of movement, usually rotational, of a patient of his or her surroundings. This is often accompanied by vomiting, sweating, and pallor...

Recognizing and Treating Severe Acute Pancreatitis (SAP)

Approach to Severe Acute Pancreatitis

Post category:Gastroenterology
Post published:December 17, 2021

Recognition of severe acute pancreatitis (SAP) is tricky, as many of the criteria, such as Ranson, Imrie-Glasgow, and APACHE II, are determined 24 to 48 hours after presentation. This renders them unhelpful in the emergency department (ED) time frame.

Evaluation of the Patient with Bleeding and Bruising

Evaluation of Patients with Bleeding

Post category:Hematology and Oncology
Post published:December 13, 2021

Bruising and bleeding arise when there is abnormal hemostasis. Hemostasis is dependent on normal platelet number and function, an intact coagulation pathway, and normal vessel walls.

Ingested Foreign Body: When to Intervene ?

Foreign Body Aspiration - Pathogenesis and Clinical Findings

Post category:Emergency and Acute Medicine
Post published:December 9, 2021

In adults, by far and away the most common foreign body ingestion is a meat bolus impacting a preexisting anatomic structure. In children, the most common foreign body ingestion are coins.